Most recent articles published in PLoS Biology. Free, open access to all articles online.
Updated: 1 week 1 day ago
Thu, 11/13/2008 - 12:41
Nitric oxide is shown to control the pro- and anti-inflammatory functions of surfactant protein D by altering its quaternary structure via
S-nitrosylation.
Thu, 11/13/2008 - 12:41
New neurons are born throughout life in the hippocampus. Cell-type-specific, single-gene ablation in newborn neurons reveals that the kinase cdk5 regulates growth of neuronal processes, identifying a key mechanism of neuronal integration within the adult brain.
Thu, 11/13/2008 - 12:41
An approach to induce specific tolerance--an important application for the treatment of autoimmune diseases and transplant rejections--uses polyclonal T cells transduced with an inducible form of Foxp3.
Thu, 11/13/2008 - 12:41
Transcription from within open reading frames in
S. cerevisiae, which is normally repressed by many chromatin- and transcription-related factors, has the potential to be widespread and to express alternative genetic information.
Mon, 08/25/2008 - 08:18
Can organic farming and genetically engineered crops coexist in an agriculture of the future? Tony Trewavas reviews the new book
Tomorrow's Table.
Mon, 08/25/2008 - 08:18
The few animals capable of recognizing themselves in a mirror have advanced social cognition related to adopting the perspective of someone else.
Mon, 08/25/2008 - 08:18
The European magpie, a bird with a large brain and highly developed perspective-taking skills, shows evidence of mirror self-recognition.
Mon, 08/25/2008 - 08:18
A conserved protein kinase, Cbk-1, produces different gene expression programs in cytoplasmically connected cells by directly blocking nuclear export of the transcription factor Ace2.
Mon, 08/25/2008 - 08:18
We show that the mitochondrial DNA mutation rate in
D. melanogaster is 10X higher than the nuclear mutation rate, and that major-strand G-->A hypermutablity explains the extremely biased base composition of the mitochondrial genome.