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- Anti-folate drug resistance in Africa: meta-analysis of reported dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant genotype frequencies in African Plasmodium falciparum parasite populations
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Tag Archives: pathogen
Identification of Attractive Drug Targets in Neglected-Disease Pathogens Using an In Silico Approach
Image via Wikipedia Author Summary In cell-based drug development, researchers attempt to create drugs that kill a pathogen without necessarily understanding the details of how the drugs work. In contrast, target-based drug development entails the search for compounds that act … Continue reading
Scientists favor needles over tablets for global vaccinations
According to the World Health Organization, two billion people around the globe suffer from chronic parasitic worm infections, which, in addition to causing illness and developmental delay, are also suspected to interfere with the effectiveness of ordinary vaccines, making their … Continue reading
Posted in Vaccines
Tagged bystander, cells of the immune system, chronic infections, chronic parasitic infections, common childhood diseases, developing world, developmental delay, immune responses, journal nature, life threatening diseases, lymph node, mohrs, parasitic worm, pathogen, trudeau institute, vaccination procedures, vaccination programs, Vaccines, world health organization, worm infections
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Genetic variant offers protection against TB and leprosy
A study into why some people are more resistant than others to diseases such as tuberculosis (TB) and leprosy has identified a new genetic variant which affects susceptibility to these diseases. The findings, published today in the journal Cell, may … Continue reading
Posted in TB
Tagged adaptive immunity, aerobic bacteria, early steps, genetic variant, immune system, innate immune response, innate immunity, larvae, leprae, leprosy, line of defence, mammals, mycobacteria, pathogen, Pathogens, s south, south east asia, tuberculosis, tuberculosis tb, wellcome trust
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