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Tag Archives: innate immunity
Hepatitis B Virus Polymerase Blocks Pattern Recognition Receptor Signaling via Interaction with DDX3: Implications for Immune Evasion
Image via Wikipedia Author Summary Viral infection is sensed by the host innate immune system, which acts to limit viral infection by inducing antiviral cytokines such as the interferons. To establish infection, many viruses have strategies to evade the innate … Continue reading
Posted in Pathogens
Tagged chimpanzee, chronic infection, Conditions and Diseases, cytokines, Digestive Disorders, hbv, Health, hepatitis, hepatitis B, hepatitis b virus, immune evasion, Infection, innate immune response, innate immune system, innate immunity, interaction, interferons, Liver, pattern recognition, polymerase, stealth virus, viral infection, virus, vitro
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Human Complement Regulators C4b-Binding Protein and C1 Esterase Inhibitor Interact with a Novel Outer Surface Protein of Borrelia recurrentis
Author Summary Borrelia recurrentis, the causal agent of louse-borne relapsing fever is transmitted to humans via infected body lice. Infection with B. recurrentis has been achieved only in humans and is accompanied by a systemic inflammatory disease, multiple relapses of … Continue reading
Posted in Neglected tropical disease
Tagged binding protein, body lice, borrelia recurrentis, c1 esterase inhibitor, causal agent, complement activation, evasion, human tissues, inflammatory disease, innate and adaptive immunity, innate immunity, lipoprotein, louse borne relapsing fever, new drugs, outer surface, relapses, robust tools, serum, surface protein, virulence factor
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Genetic variant offers protection against TB and leprosy
A study into why some people are more resistant than others to diseases such as tuberculosis (TB) and leprosy has identified a new genetic variant which affects susceptibility to these diseases. The findings, published today in the journal Cell, may … Continue reading
Posted in TB
Tagged adaptive immunity, aerobic bacteria, early steps, genetic variant, immune system, innate immune response, innate immunity, larvae, leprae, leprosy, line of defence, mammals, mycobacteria, pathogen, Pathogens, s south, south east asia, tuberculosis, tuberculosis tb, wellcome trust
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How pathogens have shaped genes involved in our immune system
A recent study on human genetics on various populations across the world conducted by researchers from the Institut Pasteur and the CNRS has shown how pathogens can shape the patterns of genetic diversity of our immune system over time. Results … Continue reading
